Long COVID signs analysis, from mind fog to persistent fatigue : Short Wave : NPR

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Long COVID signs analysis, from mind fog to persistent fatigue : Short Wave : NPR


Millions of persons are affected by lengthy COVID, a illness that encompasses a spread of signs — every thing from mind fog to persistent fatigue — and that manifests in a different way throughout sufferers.

The Washington Post/The Washington Post through Getty Images


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The Washington Post/The Washington Post through Getty Images


Millions of persons are affected by lengthy COVID, a illness that encompasses a spread of signs — every thing from mind fog to persistent fatigue — and that manifests in a different way throughout sufferers.

The Washington Post/The Washington Post through Getty Images

At a current Senate listening to on lengthy COVID, Rachel Beale took to the stage and shared her expertise managing her signs for the previous three years. “Long COVID has affected each a part of my life,” mentioned the Virginia resident. “I get up day by day feeling drained, nauseous and dizzy. I instantly begin planning once I can lay down once more.”

Beale is much from alone.

Many of her experiences have been echoed by others coping with lengthy COVID. It’s a constellation of debilitating signs that vary from mind fog and intense bodily fatigue to despair and anxiousness. Many folks have misplaced months or years to this sickness and describe excessive frustration on the lack of solutions.

Doctors, too, really feel unmoored by the dearth of solutions. “You do form of really feel such as you’re out within the wilderness,” says Rasika Karnik, the medical director of UChicago Medicine’s post-COVID. “It’s onerous to look a affected person within the eyes and say ‘we’re not fairly positive but’ and to maintain repeating that.”

There are presently no validated remedies for lengthy COVID. There is just not a extensively established biomarker that can be utilized to diagnose it. Care clinics are onerous to get into — and even if you happen to do get in, most scientists consider this is not only one sickness within the first place.

But there’s new, promising analysis that sheds gentle onto some lengthy COVID signs. In one research on bodily fatigue, researchers at Vrije University in Amsterdam in contrast muscle biopsies of sufferers with and with out lengthy COVID and located that the issue lies not with lung or coronary heart functioning, however with the muscular tissues’ talents to take up oxygen within the blood.

And one other group of researchers on the University of Pennsylvania had been capable of pinpoint one attainable explanation for mind fog: a drop in serotonin ranges. They had been additionally capable of reverse mind fog signs in mice.

There is a rising community of scientists who’re pushing analysis ahead — many with personal funding from philanthropists. Congress has allotted greater than a billion {dollars} for lengthy COVID analysis, and there is been some new funding introduced by the NIH not too long ago. But affected person advocates say that fixing an issue of this scale will take continued consideration and much more funding.

Have extra COVID questions you need us to cowl? Email us at shortwave@npr.org — we would love to listen to from you.

Listen to Short Wave on Spotify, Apple Podcasts and Google Podcasts.

Listen to each episode of Short Wave sponsor-free and assist our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.

This episode was produced by Margaret Cirino. It was edited by Brit Hanson and Rebecca Ramirez. David Greenburg was the audio engineer.

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