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I’ve beforehand reviewed the similarities between the flavonoid quercetin and the drug hydroxychloroquine, discussing the potential of utilizing quercetin in lieu of the drug in opposition to COVID-19. We’re now additionally beginning to see quercetin talked about extra typically within the scientific literature on COVID-19.
For instance, a overview article1 revealed within the June 19, 2020, concern of Frontiers in Immunology highlights quercetin’s usefulness as a COVID-19 therapy, particularly along with vitamin C. Quercetin can also be featured in a overview2 of rising COVID-19 analysis revealed within the Integrative Medicine journal. As reported by MedPage Today:3
“Quercetin … promotes SIRT2, which then inhibits the NLRP3 inflammasome meeting concerned with COVID-19 an infection, mentioned Samuel F. Yanuck, DC, of the Program on Integrative Medicine on the University of North Carolina Chapel Hill School of Medicine, who co-authored a overview4 of rising analysis on the topic. It additionally performs a job in facilitating zinc transportation throughout lipid membranes, Yanuck mentioned.
‘It’s not a bizarre or experimental substance and given it has these potential important biological roles, I think it’s worth being considered as part of an overall strategy,’ Yanuck instructed MedPage Today, including that quercetin would have to be one a part of a multifactorial therapy routine …
COVID-19 has been related to excessive ranges of interleukin-6, depleted ranges of interferons, and a cytokine storm that damages the physique and is expounded to respiratory failure, mentioned Ruben Colunga Biancatelli, MD, of Old Dominion University in Norfolk, Virginia, and first creator of a paper on quercetin and vitamin C as a possible remedy for treating SARS-CoV-2 in Frontiers in Immunology.5