Let Robots Do Your Lab Work

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Let Robots Do Your Lab Work



Dina Genkina: Hi. I’m Dina Genkina for IEEE Spectrum‘s Fixing the Future. Before we start, I want to tell you that you can get the latest coverage from some of Spectrum’s most vital beeps, together with AI, Change, and Robotics, by signing up for considered one of our free newsletters. Just go to spectrum.ieee.orgnewsletters to subscribe. Today, a visitor is Dr. Benji Maruyama, a Principal Materials Research Engineer on the Air Force Research Laboratory, or AFRL. Dr. Maruyama is a supplies scientist, and his analysis focuses on carbon nanotubes and making analysis go quicker. But he’s additionally a person with a dream, a dream of a world the place science isn’t one thing achieved by a choose few locked away in an ivory tower, however one thing most individuals can take part in. He hopes to start out what he calls the billion scientist motion by constructing AI-enabled analysis robots which can be accessible to all. Benji, thanks for approaching the present.

Benji Maruyama: Thanks, Dina. Great to be with you. I respect the invitation.

Genkina: Yeah. So let’s set the scene a bit of bit for our listeners. So you advocate for this billion scientist motion. If every thing works amazingly, what would this appear to be? Paint us an image of how AI will assist us get there.

Maruyama: Right, nice. Thanks. Yeah. So one of many issues as you set the scene there may be proper now, to be a scientist, most individuals have to have entry to a giant lab with very costly gear. So I believe prime universities, authorities labs, business of us, plenty of gear. It’s like 1,000,000 {dollars}, proper, to get considered one of them. And frankly, simply not that many people have entry to these sorts of devices. But on the identical time, there’s in all probability lots of us who wish to do science, proper? And so how will we make it in order that anybody who needs to do science can strive, can have entry to devices in order that they will contribute to it. So that’s the fundamentals behind citizen science or democratization of science so that everybody can do it. And a technique to think about it’s what occurred with 3D printing. It was once that so as to make one thing, you needed to have entry to a machine store or possibly get fancy instruments and dyes that might value tens of hundreds of {dollars} a pop. Or should you needed to do electronics, you needed to have entry to very costly gear or companies. But when 3D printers got here alongside and have become very cheap, rapidly now, anybody with entry to a 3D printer, so possibly in a college or a library or a makerspace might print one thing out. And it might be one thing enjoyable, like a sport piece, but it surely may be one thing that received you to an invention, one thing that was possibly helpful to the neighborhood, was both a prototype or an precise working machine.

And so actually, 3D printing democratized manufacturing, proper? It made it in order that many extra of us might do issues that earlier than solely a choose few might. And in order that’s the place we’re attempting to go along with science now, is that as a substitute of solely these of us who’ve entry to huge labs, we’re constructing analysis robots. And once I say we, we’re doing it, however now there are lots of others who’re doing it as nicely, and I’ll get into that. But the instance that we’ve got is that we took a 3D printer you could purchase off the web for lower than $300. Plus a few additional components, a webcam, a Raspberry Pi board, and a tripod actually, so solely 4 parts. You can get all of them for $300. Load them with open-source software program that was developed by AFIT, the Air Force Institute of Technology. So Burt Peterson and Greg Captain [inaudible]. We labored collectively to construct this absolutely autonomous 3D printing robotic that taught itself find out how to print to raised than producer’s specs. So that was a extremely enjoyable advance for us, and now we’re attempting to take that very same thought and broaden it. So I’ll flip it again over to you.

Genkina: Yeah, okay. So possibly let’s speak a bit of bit about this automated analysis robotic that you just’ve made. So proper now, it really works with a 3D printer, however is the massive image that sooner or later it’s going to present individuals entry to that million greenback lab? How would that appear to be?

Maruyama: Right, so there are completely different fashions on the market. One, we simply did a workshop on the University of— sorry, North Carolina State University about that very downside, proper? So there’s two fashions. One is to get low-cost scientific instruments just like the 3D printer. There’s a few completely different chemistry robots, one out of University of Maryland and NIST, one out of University of Washington which can be within the form of 300 to 1,000 {dollars} vary that makes it accessible. The different half is type of the consumer facility mannequin. So within the US, the Department of Energy National Labs have many consumer services the place you may apply to get time on very costly devices. Now we’re speaking tens of hundreds of thousands. For instance, Brookhaven has a synchrotron gentle supply the place you may enroll and it doesn’t value you any cash to make use of the ability. And you will get days on that facility. And in order that’s already there, however now the advances are that by utilizing this, autonomy, autonomous closed loop experimentation, that the work that you just do will probably be a lot quicker and way more productive. So, for instance, on ARES, our Autonomous Research System at AFRL, we really have been in a position to do experiments so quick {that a} professor who got here into my lab stated, it simply took me apart and stated, “Hey, Benji, in a week’s worth of time, I did a dissertation’s worth of research.” So possibly 5 years price of analysis in every week. So think about should you hold doing that week after week after week, how briskly analysis goes. So it’s very thrilling.

Genkina: Yeah, so inform us a bit of bit about how that works. So what’s this technique that has sped up 5 years of analysis into every week and made graduate college students out of date? Not but, not but. How does that work? Is that the 3D printer system or is {that a}—

Maruyama: So we began with our system to develop carbon nanotubes. And I’ll say, really, after we first considered it, your remark about graduate college students being absolute— out of date, sorry, is attention-grabbing and vital as a result of, after we first constructed our system that labored it 100 occasions quicker than regular, I assumed that is perhaps the case. We referred to as it form of graduate scholar out of the loop. But once I began speaking with individuals who specialise in autonomy, it’s really the alternative, proper? It’s really empowering graduate college students to go quicker and likewise to do the work that they wish to do, proper? And so simply to digress a bit of bit, if you consider farmers earlier than the Industrial Revolution, what have been they doing? They have been plowing fields with oxen and beasts of burden and hand plows. And it was exhausting work. And now, after all, you wouldn’t ask a farmer as we speak to surrender their tractor or their mix harvester, proper? They would say, after all not. So very quickly, we count on it to be the identical for researchers, that should you requested a graduate scholar to surrender their autonomous analysis robotic 5 years from now, they’ll say, “Are you crazy? This is how I get my work done.”

But for our authentic ARES system, it labored on the synthesis of carbon nanotubes. So that meant that what we’re doing is attempting to take this technique that’s been fairly nicely studied, however we haven’t found out find out how to make it at scale. So at a whole lot of hundreds of thousands of tons per 12 months, form of like polyethylene manufacturing. And a part of that’s as a result of it’s sluggish, proper? One experiment takes a day, but in addition as a result of there are simply so many various methods to do a response, so many various combos of temperature and strain and a dozen completely different gases and half the periodic desk so far as the catalyst. It’s simply an excessive amount of to only brute power your manner by. So despite the fact that we went from experiments the place we might do 100 experiments a day as a substitute of 1 experiment a day, simply that combinatorial house was vastly overwhelmed our skill to do it, even with many analysis robots or many graduate college students. So the concept of getting artificial intelligence algorithms that drive the analysis is essential. And in order that skill to do an experiment, see what occurred, after which analyze it, iterate, and continuously have the ability to select the optimum subsequent greatest experiment to do is the place ARES actually shines. And in order that’s what we did. ARES taught itself find out how to develop carbon nanotubes at managed charges. And we have been the primary ones to try this for materials science in our 2016 publication.

Genkina: That’s very thrilling. So possibly we are able to peer underneath the hood a bit of little bit of this AI mannequin. How does the magic work? How does it decide the following greatest level to take and why it’s higher than you possibly can do as a graduate scholar or researcher?

Maruyama: Yeah, and so I believe it’s attention-grabbing, proper? In science, lots of occasions we’re taught to carry every thing fixed, change one variable at a time, search over that complete house, see what occurred, after which return and take a look at one thing else, proper? So we cut back it to 1 variable at a time. It’s a reductionist method. And that’s labored very well, however lots of the issues that we wish to go after are just too advanced for that reductionist method. And so the advantage of with the ability to use synthetic intelligence is that top dimensionality isn’t any downside, proper? Tens of dimensions search over very advanced high-dimensional parameter house, which is overwhelming to people, proper? Is simply principally bread and butter for AI. The different half to it’s the iterative half. The great thing about doing autonomous experimentation is that you just’re continuously iterating. You’re continuously studying over what simply occurred. You may additionally say, nicely, not solely do I do know what occurred experimentally, however I’ve different sources of prior information, proper? So for instance, excellent gasoline legislation says that this could occur, proper? Or Gibbs section rule may say, this could occur or this could’t occur. So you should use that prior information to say, “Okay, I’m not going to do those experiments because that’s not going to work. I’m going to try here because this has the best chance of working.”

And inside that, there are a lot of completely different machine studying or synthetic intelligence algorithms. Bayesian optimization is a well-liked one that can assist you select what experiment is greatest. There’s additionally new AI that individuals are attempting to develop to get higher search.

Genkina: Cool. And so the software program a part of this autonomous robotic is obtainable for anybody to obtain, which can be actually thrilling. So what would somebody have to do to have the ability to use that? Do they should get a 3D printer and a Raspberry Pi and set it up? And what would they have the ability to do with it? Can they only construct carbon nanotubes or can they do extra stuff?

Maruyama: Right. So what we did, we constructed ARES OS, which is our open supply software program, and we’ll make certain to get you the GitHub hyperlink in order that anybody can obtain it. And the concept behind ARES OS is that it offers a software program framework for anybody to construct their very own autonomous analysis robotic. And so the 3D printing instance will probably be on the market quickly. But it’s the start line. Of course, if you wish to construct your personal new type of robotic, you continue to should do the software program improvement, for instance, to hyperlink the ARES framework, the core, if you’ll, to your specific {hardware}, possibly your specific digital camera or 3D printer, or pipetting robotic, or spectrometer, no matter that’s. We have examples on the market and we’re hoping to get to a degree the place it turns into way more user-friendly. So having direct Python connects so that you just don’t— presently it’s programmed in C#. But to make it extra accessible, we’d prefer it to be arrange in order that if you are able to do Python, you may in all probability have good success in constructing your personal analysis robotic.

Genkina: Cool. And you’re additionally engaged on a academic model of this, I perceive. So what’s the standing of that and what’s completely different about that model?

Maruyama: Yeah, proper. So the tutorial model goes to be– its form of composition of a mix of {hardware} and software program. So what we’re beginning with is a low-cost 3D printer. And we’re collaborating now with the University at Buffalo, Materials Design Innovation Department. And we’re hoping to construct up a robotic primarily based on a 3D printer. And we’ll see the way it goes. It’s nonetheless evolving. But for instance, it might be primarily based on this very cheap $200 3D printer. It’s an Ender 3D printer. There’s one other printer on the market that’s primarily based on University of Washington’s Jubilee printer. And that’s a really thrilling improvement as nicely. So professors Lilo Pozzo and Nadya Peek on the University of Washington constructed this Jubilee robotic with that concept of accessibility in thoughts. And so combining our ARES OS software program with their Jubilee robotic {hardware} is one thing that I’m very enthusiastic about and hope to have the ability to transfer ahead on.

Genkina: What’s this Jubilee 3D printer? How is it completely different from an everyday 3D printer?

Maruyama: It’s very open supply. Not all 3D printers are open supply and it’s primarily based on a gantry system with interchangeable heads. So for instance, you will get not only a 3D printing head, however different heads that may do issues like do indentation, see how stiff one thing is, or possibly put a digital camera on there that may transfer round. And so it’s the pliability of with the ability to decide completely different heads dynamically that I believe makes it tremendous helpful. For the software program, proper, we’ve got to have a superb, accessible, user-friendly graphical consumer interface, a GUI. That takes effort and time, so we wish to work on that. But once more, that’s simply the {hardware} software program. Really to make ARES a superb academic platform, we have to make it so {that a} trainer who’s can have the bottom activation barrier doable, proper? We need he or she to have the ability to pull a lesson plan off of the web, have supporting YouTube movies, and truly have the fabric that could be a absolutely developed curriculum that’s mapped in opposition to state requirements.

So that, proper now, should you’re a trainer who— let’s face it, lecturers are already overwhelmed with all that they should do, placing one thing like this into their curriculum will be lots of work, particularly if you need to take into consideration, nicely, I’m going to take all this time, however I even have to satisfy all of my educating requirements, all of the state curriculum requirements. And so if we construct that out in order that it’s a matter of simply wanting on the curriculum and simply checking off the containers of what state requirements it maps to, then that makes it that a lot simpler for the trainer to show.

Genkina: Great. And what do you suppose is the timeline? Do you count on to have the ability to do that someday within the coming 12 months?

Maruyama: That’s proper. These issues all the time take longer than hoped for than anticipated, however we’re hoping to do it inside this calendar 12 months and really excited to get it going. And I’d say on your listeners, should you’re thinking about working collectively, please let me know. We’re very enthusiastic about attempting to contain as many individuals as we are able to.

Genkina: Great. Okay, so you might have the tutorial model, and you’ve got the extra analysis geared model, and also you’re engaged on making this academic model extra accessible. Is there one thing with the analysis model that you just’re engaged on subsequent, the way you’re hoping to improve it, or is there one thing you’re utilizing it for proper now that you just’re enthusiastic about?

There’s numerous issues that we’re very enthusiastic about the potential for carbon nanotubes being produced at very giant scale. So proper now, individuals might bear in mind carbon nanotubes as that nice materials that form of by no means made it and was very overhyped. But there’s a core group of us who’re nonetheless engaged on it due to the vital promise of that materials. So it’s materials that’s tremendous robust, stiff, light-weight, electrically conductive. Much higher than silicon as a digital electronics compute materials. All of these nice issues, besides we’re not making it at giant sufficient scale. It’s really used fairly considerably in lithium-ion batteries. It’s an vital software. But apart from that, it’s form of like the place’s my flying automobile? It’s by no means panned out. But there’s, as I stated, a bunch of us who’re working to actually produce carbon nanotubes at a lot bigger scale. So giant scale for nanotubes now could be form of within the kilogram or ton scale. But what we have to get to is a whole lot of hundreds of thousands of tons per 12 months manufacturing charges. And why is that? Well, there’s an awesome effort that got here out of ARPA-E. So the Department of Energy Advanced Research Projects Agency and the E is for Energy in that case.

So they funded a collaboration between Shell Oil and Rice University to pyrolyze methane, so pure gasoline into hydrogen for the hydrogen financial system. So now that’s a clear burning gas plus carbon. And as a substitute of burning the carbon to CO2, which is what we now do, proper? We simply take pure gasoline and feed it by a turbine and generate electrical energy as a substitute of— and that, by the way in which, generates a lot CO2 that it’s inflicting world local weather change. So if we are able to try this pyrolysis at scale, at a whole lot of hundreds of thousands of tons per 12 months, it’s actually a save the world proposition, which means that we are able to keep away from a lot CO2 emissions that we are able to cut back world CO2 emissions by 20 to 40 %. And that’s the save the world proposition. It’s an enormous endeavor, proper? That’s a giant downside to deal with, beginning with the science. We nonetheless don’t have the science to effectively and successfully make carbon nanotubes at that scale. And then, after all, we’ve got to take the fabric and switch it into helpful merchandise. So the batteries is the primary instance, however eager about changing copper for electrical wire, changing metal for structural supplies, aluminum, all these sorts of functions. But we are able to’t do it. We can’t even get to that type of improvement as a result of we haven’t been in a position to make the carbon nanotubes at enough scale.

So I’d say that’s one thing that I’m engaged on now that I’m very enthusiastic about and attempting to get there, but it surely’s going to take some good developments in our analysis robots and a few very good individuals to get us there.

Genkina: Yeah, it appears so counterintuitive that making every thing out of carbon is nice for decreasing carbon emissions, however I suppose that’s the break.

Maruyama: Yeah, it’s attention-grabbing, proper? So individuals discuss carbon emissions, however actually, the molecule that’s inflicting world warming is carbon dioxide, CO2, which you get from burning carbon. And so should you take that methane and parallelize it to carbon nanotubes, that carbon is now sequestered, proper? It’s not going off as CO2. It’s staying in stable state. And not solely is it simply not going up into the ambiance, however now we’re utilizing it to switch metal, for instance, which, by the way in which, metal, aluminum, copper manufacturing, all of these issues emit plenty of CO2 of their manufacturing, proper? They’re power intensive as a fabric manufacturing. So it’s type of ironic.

Genkina: Okay, and are there some other analysis robots that you just’re enthusiastic about that you just suppose are additionally contributing to this democratization of science course of?

Maruyama: Yeah, so we talked about Jubilee, the NIST robotic, which is from Professor Ichiro Takeuchi at Maryland and Gilad Kusne at NIST, National Institute of Standards and Technology. Theirs is enjoyable too. It’s LEGO as. So it’s really primarily based on a LEGO robotics platform. So it’s an precise chemistry robotic constructed out of Legos. So I believe that’s enjoyable as nicely. And you may think about, identical to we’ve got LEGO robotic competitions, we are able to have autonomous analysis robotic competitions the place we attempt to do analysis by these robots or competitions the place all people form of begins with the identical robotic, identical to with LEGO robotics. So that’s enjoyable as nicely. But I’d say there’s a rising variety of individuals doing these sorts of, to start with, low-cost science, accessible science, however specifically low-cost autonomous experimentation.

Genkina: So how far are we from a world the place a highschool scholar has an thought they usually can simply go and carry it out on some autonomous analysis system at some high-end lab?

Maruyama: That’s a extremely good query. I hope that it’s going to be in 5 to 10 years, that it turns into moderately commonplace. But it’s going to take nonetheless some vital funding to get this going. And so we’ll see how that goes. But I don’t suppose there are any scientific impediments to getting this achieved. There is a big quantity of engineering to be achieved. And generally we hear, oh, it’s simply engineering. The engineering is a big downside. And it’s work to get a few of these issues accessible, low value. But there are many nice efforts. There are individuals who have used CDs, compact discs to make spectrometers out of. There are plenty of good examples of citizen science on the market. But it’s, I believe, at this level, going to take funding in software program, in {hardware} to make it accessible, after which importantly, getting college students actually on top of things on what AI is and the way it works and the way it may also help them. And so I believe it’s really actually vital. So once more, that’s the democratization of science is that if we are able to make it out there to everybody and accessible, then that helps individuals, everybody contribute to science. And I do consider that there are vital contributions to be made by atypical residents, by individuals who aren’t you understand PhDs working in a lab.

And I believe there’s lots of science on the market to be achieved. If you ask working scientists, nearly nobody has run out of concepts or issues they wish to work on. There’s many extra scientific issues to work on than we’ve got the time the place individuals are funding to work on. And so if we make science cheaper to do, then rapidly, extra individuals can do science. And so these questions begin to be resolved. And so I believe that’s tremendous vital. And now we’ve got, as a substitute of, simply these of us who work in huge labs, you might have hundreds of thousands, tens of hundreds of thousands, as much as a billion individuals, that’s the billion scientist thought, who’re contributing to the scientific neighborhood. And that, to me, is so highly effective that many extra of us can contribute than simply the few of us who do it proper now.

Genkina: Okay, that’s an awesome place to finish on, I believe. So, as we speak we spoke to Dr. Benji Maruyama, a fabric scientist at AFRL, about his efforts to democratize scientific discovery by automated analysis robots. For IEEE Spectrum, I’m Dina Genkina, and I hope you’ll be a part of us subsequent time on Fixing the Future.

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